chronic obstructive pulmonary — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1532	Pidotimod		Others , Antibacterial
	Pidotimod is a synthetic dipeptide with immunomodulatory properties.		Others , Antibacterial
T6054	GSK256066		PDE
	GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.		PDE
TN1355	Acanthoside B		Immunology/Inflammation related
	Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.		Immunology/Inflammation related
T30258	AZD-4818	CCR1 antagonist	CCR
	AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.		CCR
T4503	Talniflumate	Somalgen	Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
	Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T22245	Arformoterol Tartrate	(R,R)-Formoterol tartrate	Adrenergic Receptor
	Arformoterol Tartrate ((R,R)-Formoterol tartrate) is the tartrate salt of arformoterol. Arformoterol is a long-acting beta-2 adrenergic agonist with bronchodilator activity[2].		Adrenergic Receptor
T1083	Theophylline	Theo-24,1,3-Dimethylxanthine	Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
	Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T6445	Cilomilast	SB-207499,Ariflo	PDE
	Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.		PDE
T6547	Ipratropium Bromide	Sch 1000,Itrop,Atrovent	AChR
	Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.		AChR
T0794	Mepenzolate Bromide	Colibantil,Cantil,Cantilaque	AChR
	Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.		AChR
T26795	PXS-4728A	BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl	Monoamine Oxidase
	BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].		Monoamine Oxidase
T0098	Ipratropium bromide monohydrate	Ipratropium bromide hydrate	AChR
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial...		AChR
T21389	Enprofylline	Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum	Others
	Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick...		Others
T1083L	Theophylline monohydrate	Quibron	HDAC , PDE , Adenosine Receptor
	Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...		HDAC , PDE , Adenosine Receptor
T34387	Ronomilast	ELB353,ELB 353,ELB-353,Elbimilast
	Ronomilast(Elbimilast, ELB 353) is a PDE4 inhibitor for chronic inflammatory disease. Ronomilast is developed to treat chronic obstructive pulmonary disease (COPD).
T33386	Milveterol HCl	Milveterol,GSK-159797,GSK 159797,GSK159797	Adrenergic Receptor
	Milveterol HCl is a long-acting β(2) -adrenergic receptor agonist for the potential treatment of chronic obstructive pulmonary disease (COPD).		Adrenergic Receptor
T26760	Bedoradrine sulfate	KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246	Adrenergic Receptor
	Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease.		Adrenergic Receptor
T83168	Aderamastat	FP-025	MMP
	Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis [1].		MMP
T12850	Dilmapimod	SB-681323,GW 681323	p38 MAPK , Autophagy
	Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.		p38 MAPK , Autophagy
T9877	Tiquizium		AChR
	Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.		AChR